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Sovilnesib
CAS No. 2410796-79-9
Sovilnesib( AMG 650 )
Catalog No. M28250 CAS No. 2410796-79-9
Sovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 258 | In Stock |
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| 5MG | 235 | In Stock |
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| 10MG | 376 | In Stock |
|
| 25MG | 630 | In Stock |
|
| 50MG | 879 | In Stock |
|
| 100MG | 1190 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSovilnesib
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NoteResearch use only, not for human use.
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Brief DescriptionSovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.
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DescriptionSovilnesib is a kinesin-like protein KIF18A inhibitor (WO2020132648). Sovilnesib can be used for the research of cancer.(In Vitro):Sovilnesib is a kinesin-like protein KIF18A inhibitor.
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In VitroCell Viability Assay Cell Line:Cancer cell lines Concentration:0-10 pM Incubation Time:96 and 144 hours Result:Inhibited tumor cell growth in a dose-dependent manner.
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In VivoAnimal Model:Female nude mice without thymus with OVCAR-3 xenografts Dosage:10, 30, and 100 mg/kg Administration:Oral administration; daily, for 45 days Result:Had antitumor efficacy in a dose-dependent manner.
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SynonymsAMG 650
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorHistamine relase
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Research Area——
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Indication——
Chemical Information
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CAS Number2410796-79-9
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Formula Weight564.65
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Molecular FormulaC26H34F2N6O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (177.10 mM)
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SMILESCc1cc(NC(c(ccc(NS(CCO)(=O)=O)c2)c2N2CCC3(CC3)CC2)=O)nc(N(CC2)CCC2(F)F)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Watt GD, et al. Protective effect opf lodoxamide tromethamine on allergen inhalation challenge. J Allergy Clin Immunol. 1980 Oct;66(4):286-94.
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