ARV-471( —— )

Catalog No. M28234 CAS No. 2229711-68-4

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Datasheet

HNMR

HPLC

MSDS

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Product Name

ARV-471
Note

Research use only, not for human use.
Brief Description

ARV-471 is a best-in-class, orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
Description

ARV-471 is a best-in-class, orally active Cereblon -based estrogen receptor ( ER ) PROTAC degrader. ARV-471 is developed for the research of breast cancer.
In Vitro

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In Vivo

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Synonyms

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Pathway

Endocrinology/Hormones
Target

Estrogen Receptor/ERR
Recptor

nAChR
Research Area

——
Indication

——

CAS Number

2229711-68-4
Formula Weight

723.9
Molecular Formula

C45H49N5O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 110 mg/mL (151.95 mM)
SMILES

Oc1cc(CC[C@@H]([C@@H]2c(cc3)ccc3N3CCC(CN(CC4)CCN4c(cc4)cc(CN5[C@@H](CCC(N6)=O)C6=O)c4C5=O)CC3)c3ccccc3)c2cc1
Chemical Name

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1.Matthew J. Cheesman . Oceania: Antidepressant Medicinal Plants. Herbal Medicine in Depression. 2016, 483-527.

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