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CMP8
CAS No. 851107-28-3
CMP8( —— )
Catalog No. M26655 CAS No. 851107-28-3
CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 371 | In Stock |
|
| 5MG | 296 | In Stock |
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| 10MG | 424 | In Stock |
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| 25MG | 656 | In Stock |
|
| 50MG | 865 | In Stock |
|
| 100MG | 1097 | In Stock |
|
| 200MG | 1469 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCMP8
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NoteResearch use only, not for human use.
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Brief DescriptionCMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD).
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DescriptionCMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively.(In Vivo):CMP8 is dosed in male Balb-c mice (4 mg/kg, ip). In mammalian cells, the plasma concentration after 4 h is 1.5-fold its EC50. It has a Cmax of 0.5 μM after 30 min.
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In Vitro——
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In VivoCMP8 (Compound 20h) is dosed in male Balb-c mice (4 mg/kg, ip). The plasma concentration after 4 h is 1.5-fold its EC50 in mammalian cells with a Cmax of 0.5 μM after 30 min.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetEstrogen Receptor/ERR
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number851107-28-3
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Formula Weight528.09
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Molecular FormulaC33H34ClNO3
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Purity>98% (HPLC)
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Solubility——
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SMILESOc1ccc2C3=C(C(=O)CCC3(Cc3ccc(Cl)cc3)Cc2c1)c1ccc(OCCN2CCCCC2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu WN, et al. Biotransformation of an antihypertensive arylalkylamine analogue in the rat. Xenobiotica. 1998 Oct;28(10):957-72.
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