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AKR1C3-IN-4

CAS No. 1284180-11-5

AKR1C3-IN-4( —— )

Catalog No. M28198 CAS No. 1284180-11-5

AKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC 50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
10MG 30 In Stock
25MG 45 In Stock
50MG 61 In Stock
100MG 87 In Stock
200MG 129 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    AKR1C3-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    AKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC 50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
  • Description
    AKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC 50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.(In Vitro):AKR1C3-IN-4 has an IC 50 of 15.1 μM for AKR1C2 .
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    NADPH
  • Recptor
    Antibiotic
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1284180-11-5
  • Formula Weight
    281.234
  • Molecular Formula
    C14H10F3NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (355.58 mM)
  • SMILES
    OC(=O)c1cccc(Nc2ccc(cc2)C(F)(F)F)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hazra S, et al. Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis. Biochemistry. 2014 Jun 10;53(22):3671-8.
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