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AKR1C3-IN-4
CAS No. 1284180-11-5
AKR1C3-IN-4( —— )
Catalog No. M28198 CAS No. 1284180-11-5
AKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC 50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 10MG | 30 | In Stock |
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| 25MG | 45 | In Stock |
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| 50MG | 61 | In Stock |
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| 100MG | 87 | In Stock |
|
| 200MG | 129 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAKR1C3-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionAKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC 50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
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DescriptionAKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC 50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.(In Vitro):AKR1C3-IN-4 has an IC 50 of 15.1 μM for AKR1C2 .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetNADPH
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RecptorAntibiotic
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Research Area——
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Indication——
Chemical Information
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CAS Number1284180-11-5
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Formula Weight281.234
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Molecular FormulaC14H10F3NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (355.58 mM)
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SMILESOC(=O)c1cccc(Nc2ccc(cc2)C(F)(F)F)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hazra S, et al. Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis. Biochemistry. 2014 Jun 10;53(22):3671-8.
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