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3-Phenyltoxoflavin
CAS No. 32502-63-9
3-Phenyltoxoflavin( ZINC267655 | Phenyltoxoflavin )
Catalog No. M28065 CAS No. 32502-63-9
3-Phenyltoxoflavin is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 128 | In Stock |
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| 5MG | 117 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 337 | In Stock |
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| 50MG | 500 | In Stock |
|
| 100MG | 737 | In Stock |
|
| 200MG | 1014 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name3-Phenyltoxoflavin
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NoteResearch use only, not for human use.
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Brief Description3-Phenyltoxoflavin is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.
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Description3-Phenyltoxoflavin is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.(In Vitro):3-Phenyltoxoflavin (0.56 nM-100 μM) dose-dependently competes with biotinylated Hsp90 peptide for binding to TPR2A. In BT474 cells, 3-Phenyltoxoflavin (1 nM-100 μM) dose-dependently inhibits cell proliferation with an IC50 of 690 nM.
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In Vitro3-Phenyltoxoflavin (1 nM-100 μM; 4 d) inhibits BT474 cells proliferation in a concentration-dependent manner, with an IC50 of 690 nM.3-Phenyltoxoflavin (0.56 nM-100 μM; 2 h) competes with biotinylated Hsp90 peptide for its binding to TPR2A in a dose-dependent manner.
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In Vivo——
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SynonymsZINC267655 | Phenyltoxoflavin
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number32502-63-9
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Formula Weight269.26
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Molecular FormulaC13H11N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 7.14 mg/mL (26.52 mM)
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SMILESO=C1N=C2C(=NC(=NN2C)C3=CC=CC=C3)C(=O)N1C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ajeet. QSAR Study of Methionine Aminopeptidase Inhibitors as Anti-cancer Agents Using MLR Approach[J]. american journal of pharmacological sciences. 2013;1(5):80-83, 4 pp.
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