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Mesendogen

CAS No. 864716-85-8

Mesendogen( —— )

Catalog No. M27900 CAS No. 864716-85-8

Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 90 In Stock
5MG 80 In Stock
10MG 140 In Stock
25MG 306 In Stock
50MG 524 In Stock
100MG 737 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Mesendogen
  • Note
    Research use only, not for human use.
  • Brief Description
    Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
  • Description
    Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) and 7 (TRPM7) and acts by inhibiting TRPM6/TRPM7 magnesium channel activity.
  • In Vitro
    Western Blot Analysis Cell Line:H9 hESCs Concentration:10 μM Incubation Time:7 days Result:Downregulated expression levels of pluripotency markers OCT4 and SOX2.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    5-HT1B
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    864716-85-8
  • Formula Weight
    400.84
  • Molecular Formula
    C18H16ClF3N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (249.47 mM)
  • SMILES
    CC(C)c1ccc(cc1)C(=O)NC(=S)Nc1cc(ccc1Cl)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Knobelman DA, Kung HF, Lucki I. Regulation of extracellular concentrations of 5-hydroxytryptamine (5-HT) in mouse striatum by 5-HT(1A) and 5-HT(1B) receptors. J Pharmacol Exp Ther. 2000 Mar;292(3):1111-7
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