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Evifacotrep

CAS No. 2413739-88-3

Evifacotrep( —— )

Catalog No. M28273 CAS No. 2413739-88-3

Evifacotrep, a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Evifacotrep
  • Note
    Research use only, not for human use.
  • Brief Description
    Evifacotrep, a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases .
  • Description
    Evifacotrep, a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases .(In Vitro):Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    Raf|KRAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2413739-88-3
  • Formula Weight
    441.77
  • Molecular Formula
    C18H12ClF4N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (113.18 mM)
  • SMILES
    O=C1NN=CC(N2Cc3ncnc(Oc(cc4)c(C(F)(F)F)cc4F)c3CC2)=C1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Huestis MP, et al. Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor. ACS Med Chem Lett. 2021 Apr 21;12(5):791-797.
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