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EF24
CAS No. 342808-40-6
EF24( EF-24 | 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone )
Catalog No. M27874 CAS No. 342808-40-6
EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 81 | In Stock |
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| 5MG | 73 | In Stock |
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| 10MG | 128 | In Stock |
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| 25MG | 235 | In Stock |
|
| 50MG | 346 | In Stock |
|
| 100MG | 523 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1107 | In Stock |
|
| 1G | 1479 | In Stock |
|
Biological Information
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Product NameEF24
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NoteResearch use only, not for human use.
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Brief DescriptionEF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK.
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DescriptionEF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
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In Vitro——
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In Vivo——
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SynonymsEF-24 | 3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone
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PathwayApoptosis
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TargetPERK
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number342808-40-6
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Formula Weight347.79
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Molecular FormulaC19H16ClF2NO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (160.60 mM)
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SMILESCl.Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhang M, et al. A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance. Nat Chem Biol. 2011 Sep 4;7(10):671-7.
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