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Sonepiprazole
CAS No. 170858-33-0
Sonepiprazole( PNU-101387G | U-101387G )
Catalog No. M27715 CAS No. 170858-33-0
Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 44 | In Stock |
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| 5MG | 35 | In Stock |
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| 10MG | 57 | In Stock |
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| 25MG | 126 | In Stock |
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| 50MG | 210 | In Stock |
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| 100MG | 303 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSonepiprazole
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NoteResearch use only, not for human use.
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Brief DescriptionSonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.
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DescriptionSonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.
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In VitroSonepiprazole exhibits highly specific binding to the D4 dopamine receptor with more than 100-fold selectivity for the D4 receptor over other receptors, including dopamine, serotonin, and adrenergic receptors.
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In Vivo——
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SynonymsPNU-101387G | U-101387G
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorNOX1
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Research Area——
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Indication——
Chemical Information
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CAS Number170858-33-0
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Formula Weight401.53
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Molecular FormulaC21H27N3O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (311.32 mM)
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SMILESNS(=O)(=O)c1ccc(cc1)N1CCN(CC[C@H]2OCCc3ccccc23)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Brown SJ, et al. Probe Report for NOX1 Inhibitors. 2009 Apr 23 [updated 2010 Sep 2]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.
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