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Nitrocaramiphen hydrochloride

CAS No. 98636-73-8

Nitrocaramiphen hydrochloride( —— )

Catalog No. M27669 CAS No. 98636-73-8

Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 91 In Stock
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200MG 306 In Stock
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Biological Information

  • Product Name
    Nitrocaramiphen hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.
  • Description
    Nitrocaramiphen hydrochloride is a selective M1 muscarinic antagonist and inhibits binding to sigma sites in brain.(In Vitro):Nitrocaramiphen hydrochloride binds with high affinity for M1 sites (Ki = 5.5 nM) and with a 71-fold selectivity over M2, and a 10-fold selectivity for the M1 over the M3 subtype.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    Tubulin polymerization
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    98636-73-8
  • Formula Weight
    370.87
  • Molecular Formula
    C18H27ClN2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 10 mg/mL (26.96 mM)
  • SMILES
    Cl.CCN(CC)CCOC(=O)C1(CCCC1)c1ccc(cc1)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.R De Vincenzo, et al. Antiproliferative Activity of Colchicine Analogues on MDR-positive and MDR-negative Human Cancer Cell Lines. Anticancer Drug Des. 1998 Jan;13(1):19-33.
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