m-PEG7-Br
CAS No. 104518-25-4
m-PEG7-Br( —— )
Catalog No. M26976 CAS No. 104518-25-4
m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Namem-PEG7-Br
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NoteResearch use only, not for human use.
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Brief Descriptionm-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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Descriptionm-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor(HO)-1| Antifection| NF-κB| NO| NOS| Nrf2
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Research Area——
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Indication——
Chemical Information
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CAS Number104518-25-4
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Formula Weight403.31
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Molecular FormulaC15H31BrO7
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Purity>98% (HPLC)
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Solubility——
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SMILESCOCCOCCOCCOCCOCCOCCOCCBr
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Enpp-1-IN-1
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(-)-Isolariciresinol 9'-O-glucoside is a natural product for research related to life sciences.
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CRSP-1
Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related peptide (CGRP) and adrenomedullin receptors. Inhibits formation of multinuclear osteoclasts with similar efficacy to CT in vitro. Suppresses food intake and increases body temperature in free-feeding rats, and significantly decreases plasma calcium levels in vivo.
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