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Biotin-PEG12-NHS ester
CAS No. 1934296-88-4
Biotin-PEG12-NHS ester( —— )
Catalog No. M26902 CAS No. 1934296-88-4
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 64 | In Stock |
|
| 5MG | 38 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 93 | In Stock |
|
| 50MG | 135 | In Stock |
|
| 100MG | 200 | In Stock |
|
| 200MG | 296 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBiotin-PEG12-NHS ester
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NoteResearch use only, not for human use.
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Brief DescriptionBiotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionBiotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorArf1| Arf6
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Research Area——
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Indication——
Chemical Information
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CAS Number1934296-88-4
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Formula Weight941.1
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Molecular FormulaC41H72N4O18S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (106.26 mM)
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Benabdi S, et al. Family-wide Analysis of the Inhibition of Arf Guanine Nucleotide Exchange Factors with Small Molecules: Evidence of Unique Inhibitory Profiles. Biochemistry. 2017 Sep 26;56(38):5125-5133.
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