Protein Kinase C (530-558)

CAS No. 122613-29-0

Protein Kinase C (530-558)( ——— )

Catalog No. M40351 CAS No. 122613-29-0

Protein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Protein Kinase C (530-558)
  • Note
    Research use only, not for human use.
  • Brief Description
    Protein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.
  • Description
    Protein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.
  • In Vitro
    Protein Kinase C (530-558) (1 nM-1 μM, 24 h) causes a dose-responsive inhibition of bone resorption, which is accompanied by a rapid and distinctive change in osteoclast morphology.Cell Viability Assay Cell Line:Osteoclast cell Concentration:1 nM, 10 nM, 100 nM, 1 μM Incubation Time:24 h Result:Showed a dose-responsive, marked inhibition of bone resorption was observed between 10 nM and 1 μM. At 1 μM, resorption was inhibited by more thaln 87 %.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ———
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    122613-29-0
  • Formula Weight
    3354.7
  • Molecular Formula
    C148H220N34O51S2
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Moonga BS, et al. Effects of peptide fragments of protein kinase C on isolated rat osteoclasts. Exp Physiol. 1998 Nov;83(6):717-25.?
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