Bonaid TM

CAS No. 878006-06-5

Bonaid TM( (6)-Dehydroparadol )

Catalog No. M26527 CAS No. 878006-06-5

(E)-[6]-Dehydroparadol shows growth inhibition and induction of apoptosis against human cancer cells(IC50 values of 43.02 μM in HCT-116 cell and 41.59 μM in H-1299 cell, respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 89 In Stock
5MG 81 In Stock
10MG 112 In Stock
25MG 207 In Stock
50MG 276 In Stock
100MG 398 In Stock
200MG Get Quote In Stock
500MG 900 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Bonaid TM
  • Note
    Research use only, not for human use.
  • Brief Description
    (E)-[6]-Dehydroparadol shows growth inhibition and induction of apoptosis against human cancer cells(IC50 values of 43.02 μM in HCT-116 cell and 41.59 μM in H-1299 cell, respectively).
  • Description
    (E)-[6]-Dehydroparadol shows growth inhibition and induction of apoptosis against human cancer cells(IC50 values of 43.02 μM in HCT-116 cell and 41.59 μM in H-1299 cell, respectively).(In Vitro):(E)--Dehydroparadol (5-80 μM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 μM, respectively. (E)--Dehydroparadol (10-40 μM; 24 h) induces apoptosis in HCT-116 and H-1299 cells.(In Vivo):(E)--Dehydroparadol (5 μM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos.
  • In Vitro
    (E)--Dehydroparadol (M15) (5-80 μM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 μM, respectively.(E)--Dehydroparadol (10-40 μM; 24 h) induces apoptosis in HCT-116 and H-1299 cells.
  • In Vivo
    (E)--Dehydroparadol (compound 19) (5 μM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos.
  • Synonyms
    (6)-Dehydroparadol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    878006-06-5
  • Formula Weight
    276.376
  • Molecular Formula
    C17H24O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (361.83 mM)
  • SMILES
    CCCCCCCC(=O)\C=C\c1ccc(O)c(OC)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nakajima T, et al. [Determination of nequinate and buquinolate in livestock products using liquid chromatography-tandem mass spectrometry]. Shokuhin Eiseigaku Zasshi. 2011;52(3):178-82.
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