Selisistat R-enantiomer

CAS No. 848193-69-1

Selisistat R-enantiomer( EX-527 (R-enantiomer) )

Catalog No. M26682 CAS No. 848193-69-1

Selisistat R-enantiomer is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 283 In Stock
2MG 154 In Stock
5MG 258 In Stock
10MG 376 In Stock
25MG 630 In Stock
50MG 862 In Stock
100MG 1144 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Selisistat R-enantiomer
  • Note
    Research use only, not for human use.
  • Brief Description
    Selisistat R-enantiomer is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).
  • Description
    Selisistat R-enantiomer is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    EX-527 (R-enantiomer)
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    ERK| hERG| IFN-γ| JNK| NF-κB| p38 MAPK| STAT| TLR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    848193-69-1
  • Formula Weight
    248.71
  • Molecular Formula
    C13H13ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (402.07 mM)
  • SMILES
    NC(=O)[C@@H]1CCCc2c1[nH]c1ccc(Cl)cc21
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu XQ, et al. [Thymopolypeptides combined with matrine type alkaloids suppress HBV replication]. Zhongguo Zhong Yao Za Zhi. 2016 Apr;41(7):1275-1281. Chinese.
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