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SRT 3025
CAS No. 2070015-26-6
SRT 3025( SRT3025 )
Catalog No. M13223 CAS No. 2070015-26-6
SRT3025 is a potent, orallu actuve SIRT1 activator that activates wild-type Sirt1 protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 60 | Get Quote |
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| 10MG | 83 | Get Quote |
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| 25MG | 131 | Get Quote |
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| 50MG | 212 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSRT 3025
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NoteResearch use only, not for human use.
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Brief DescriptionSRT3025 is a potent, orallu actuve SIRT1 activator that activates wild-type Sirt1 protein.
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DescriptionSRT3025 is a potent, orallu actuve SIRT1 activator that activates wild-type Sirt1 protein, but not the Sirt1 mutant E230K; increases deacetylation of hepatic p65 and skeletal muscle Foxo1 and decreases plasma levels of LDL-cholesterol and total cholesterol and reduced atherosclerosis in vivo.Diabetes Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsSRT3025
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSirtuin
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Research AreaMetabolic Disease
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IndicationDiabetes
Chemical Information
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CAS Number2070015-26-6
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Formula Weight606.2
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Molecular FormulaC31H32ClN5O2S2
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 32 mg/mL 52.79 mM
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SMILESCOCCCC1=C(N=C(S1)C2=CC=CC=C2)C(=O)NC3=CC=CC=C3C4=NC5=C(S4)N=CC(=C5)CN6CCCC6.Cl
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Chemical Name5-(3-methoxypropyl)-2-phenyl-N-(2-(6-(pyrrolidin-1-ylmethyl)thiazolo[5,4-b]pyridin-2-yl)phenyl)thiazole-4-carboxamide hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Miranda MX, et al. Eur Heart J. 2015 Jan 1;36(1):51-9.
2. Chini CC, et al. Clin Cancer Res. 2016 May 15;22(10):2496-507.
3. Artsi H, et al. Endocrinology. 2014 Sep;155(9):3508-15.L7948:M+M7950
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