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Arimoclomol
CAS No. 289893-25-0
Arimoclomol( BRX-220 free base )
Catalog No. M26548 CAS No. 289893-25-0
Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 223 | In Stock |
|
| 5MG | 215 | In Stock |
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| 10MG | 330 | In Stock |
|
| 25MG | 548 | In Stock |
|
| 50MG | 765 | In Stock |
|
| 100MG | 1014 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameArimoclomol
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NoteResearch use only, not for human use.
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Brief DescriptionArimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
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DescriptionArimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).(In Vivo):In male Wistar rats, Arimoclomol (20 mg/kg; gavage) protects cholecystokinin-octapeptide (CCK)-induced acute pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased.
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In Vitro——
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In VivoArimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis. Animal Model:Male Wistar rats weighing 240 to 270 gDosage:20 mg/kg Administration:Administered intragastrically, for 5 daysResult:Had a protective effect against CCK-induced acute pancreatitis.
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SynonymsBRX-220 free base
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorAP-1| LOX| NF-κB| Parasite
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Research Area——
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Indication——
Chemical Information
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CAS Number289893-25-0
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Formula Weight313.78
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Molecular FormulaC14H20ClN3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO[C@@H](CO\N=C(/Cl)c1cccn(=O)c1)CN1CCCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hadjipavlou-Litina D, et al. Kukoamine A analogs with lipoxygenase inhibitory activity. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1188-93.
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