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HM03

CAS No. 500565-15-1

HM03( —— )

Catalog No. M22402 CAS No. 500565-15-1

HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 42 In Stock
5MG 38 In Stock
10MG 61 In Stock
25MG 123 In Stock
50MG 198 In Stock
100MG 323 In Stock
200MG 479 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    HM03
  • Note
    Research use only, not for human use.
  • Brief Description
    HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
  • Description
    HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
  • In Vitro
    Cell Viability Assay Cell Line:HCT116 cells Concentration:0.1, 1, 10, 25, 50 μM Incubation Time:72 hours Result:Exhibited prominent inhibition effect (18% survival at 25 μM).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    HSP
  • Recptor
    HSPA5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    500565-15-1
  • Formula Weight
    462.97
  • Molecular Formula
    C26H27ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (270.00 mM; Need ultrasonic)
  • SMILES
    COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(O)c(CN4CCN(C)CC4)c3)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Huang M , Li Z , Li D , et al. Structure-based design of HSPA5 inhibitors: From peptide to small molecule inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23(10):3044-3050.
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