7-Ketolithocholic acid( 3α-Hydroxy-7-oxo-5β-cholanic acid )

Catalog No. M26545 CAS No. 4651-67-6

7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	42	In Stock
100MG	Get Quote	In Stock
200MG	28	In Stock
500MG	38	In Stock
1G	52	In Stock

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Biological Information

Product Name

7-Ketolithocholic acid
Note

Research use only, not for human use.
Brief Description

7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
Description

7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
In Vitro

——
In Vivo

——
Synonyms

3α-Hydroxy-7-oxo-5β-cholanic acid
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

PRMT5
Research Area

——
Indication

——

Chemical Information

CAS Number

4651-67-6
Formula Weight

390.56
Molecular Formula

C24H38O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (256.04 mM)
SMILES

C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Christopher R. Smith, et al. Abstract LB003: Fragment based discovery of MRTX9768, a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors. Cancer Res 1 July 2021; 81 (13_Supplement): LB003.

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