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Home - Products - Metabolic Enzyme/Protease - IDH - Mutant IDH1-IN-2

Mutant IDH1-IN-2

CAS No. 1429176-69-1

Mutant IDH1-IN-2( —— )

Catalog No. M26311 CAS No. 1429176-69-1

Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-MS biochemical assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mutant IDH1-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-MS biochemical assay.
  • Description
    Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-MS biochemical assay.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    IDH
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1429176-69-1
  • Formula Weight
    459.542
  • Molecular Formula
    C24H31F2N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (108.81 mM)
  • SMILES
    CC(C)[C@H]1COC(=O)N1c1ccnc(N[C@@H](C)c2ccc(CN3CCC(F)(F)CC3)cc2)n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shi Q, Lu L, Lei Y, He Y, Chen J. Gland Origin and Electroantennogram Activity of Volatile Compounds in Ghost Ants, Tapinoma melanocephalum (Hymenoptera: Formicidae) and Behavioral Response to (Z)-9-Nonadecene. Environ Entomol. 2017 Dec 8;46(6):1374-1380.
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