Vorasidenib( AG-881 | AG 881 | AG881 )

Catalog No. M12509 CAS No. 1644545-52-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Vorasidenib
Note

Research use only, not for human use.
Brief Description

Vorasidenib (AG-881) is a potent, selective and orally bioavailable pan-IDH (isocitrate dehydrogenase) mutant inhibitor for treatment of AML.
Description

Vorasidenib (AG-881) is a potent, selective and orally bioavailable pan-IDH (isocitrate dehydrogenase) mutant inhibitor for treatment of AML.Blood Cancer Phase 1 Clinical.
In Vitro

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In Vivo

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Synonyms

AG-881 | AG 881 | AG881
Pathway

Metabolic Enzyme/Protease
Target

IDH
Recptor

IDH
Research Area

Cancer
Indication

Blood cancer

CAS Number

1644545-52-7
Formula Weight

414.74
Molecular Formula

C14H13ClF6N6
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 125 mg/mL 301.39 mM; H2O : < 0.1 mg/mL
SMILES

C[C@@H](NC1=NC(C2=NC(Cl)=CC=C2)=NC(N[C@H](C)C(F)(F)F)=N1)C(F)(F)F
Chemical Name

6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine