Monacolin J( Antibiotic MB 530A | Lovastatin diol lactone )

Catalog No. M26303 CAS No. 79952-42-4

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HNMR

HPLC

MSDS

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Product Name

Monacolin J
Note

Research use only, not for human use.
Brief Description

Monacolin J is a cholesterol biosynthesis inhibitor.
Description

Monacolin J is a cholesterol biosynthesis inhibitor.(In Vitro):Monacolin J is a cholesterol biosynthesis inhibitor, and inhibits the activity of HMG-CoA reductase. Na salt of Monacolin J causes 50% inhibition on reductase at 1.2 μg/mL.
In Vitro

Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase. Na salt of Monacolin J causes 50% inhibition on reductase at 1.2 μg/mL.
In Vivo

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Synonyms

Antibiotic MB 530A | Lovastatin diol lactone
Pathway

Metabolic Enzyme/Protease
Target

HMGCR
Recptor

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Research Area

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Indication

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CAS Number

79952-42-4
Formula Weight

320.42
Molecular Formula

C19H28O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (312.09 mM)
SMILES

O=C1C[C@H](O)C[C@@H](CC[C@H]2[C@@H](C)C=CC3=C[C@H](C)C[C@H](O)[C@]23[H])O1
Chemical Name

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1.Hoesl M, Dietz K, R?cken M, Berneburg M. Vitamin D levels of XP-patients under stringent sun-protection. Eur J Dermatol. 2010 Jul-Aug;20(4):457-60.

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