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EACC
CAS No. 864941-31-1
EACC( —— )
Catalog No. M26188 CAS No. 864941-31-1
EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 112 | In Stock |
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| 10MG | 199 | In Stock |
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| 25MG | 340 | In Stock |
|
| 50MG | 473 | In Stock |
|
| 100MG | 653 | In Stock |
|
| 200MG | 881 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEACC
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NoteResearch use only, not for human use.
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Brief DescriptionEACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.
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DescriptionEACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion. EACC is a reversible autophagy inhibitor.(In Vitro):EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17.EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number864941-31-1
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Formula Weight369.37
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Molecular FormulaC13H11N3O6S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 16.88 mg/mL (45.70 mM)
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SMILESCCOC(=O)NC(=O)c1ccsc1NC(=O)c1ccc(s1)[N+]([O-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yue L, Liu YJ. Mechanism of AMPPD Chemiluminescence in a Different Voice. J Chem Theory Comput. 2013 May 14;9(5):2300-12.
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