Cart
sales@molnova.com
MK-8719
CAS No. 1382799-40-7
MK-8719( —— )
Catalog No. M23538 CAS No. 1382799-40-7
MK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 277 | In Stock |
|
| 5MG | 187 | In Stock |
|
| 10MG | 312 | In Stock |
|
| 25MG | 530 | In Stock |
|
| 50MG | 733 | In Stock |
|
| 100MG | 1042 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMK-8719
-
NoteResearch use only, not for human use.
-
Brief DescriptionMK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
-
DescriptionMK-8719 is a highly potent and selective inhibitor of O-GlcNAcase (OGA) (hOGA, Ki=7.9 nM) .
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorO-GlcNAcase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1382799-40-7
-
Formula Weight268.28
-
Molecular FormulaC9H14F2N2O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESO[C@H]1[C@H](O)[C@@]2([H])N=C(NCC)S[C@@]2([H])O[C@@H]1C(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Selnick HG, et al. Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies. J Med Chem. 2019 Sep 29.
molnova catalog
related products
-
EACC
EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.?
-
Resveratrol analog 1
Resveratrol analog 1, an analog of Resveratrol, is a natural polyphenolic phytoalexin with antioxidant, anti-inflammatory, cardioprotective, and anti-cancer properties.
-
Ginkgolide K
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.
