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Duocarmycin TM

CAS No. 157922-77-5

Duocarmycin TM( —— )

Catalog No. M26182 CAS No. 157922-77-5

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Duocarmycin TM
Note

Research use only, not for human use.
Brief Description

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
Description

Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic.
In Vitro

Duocarmycin TM (60 μM; 4 d; BJAB and WSU-DLCL2 cells) is a cytotoxic agent that inhibits the proliferation of tumor cells.Cell Viability Assay Cell Line:BJAB and WSU-DLCL2 cells Concentration:60 μM Incubation Time:4 days Result:Inhibited the proliferation of tumor cells with IC50 values of 0.153 μM and 0.079μM for BJAB and WSU-DLCL2 cells, respectively.
In Vivo

——
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

DNA Alkylator
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

157922-77-5
Formula Weight

466.92
Molecular Formula

C25H23ClN2O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 50 mg/mL (107.09 mM)
SMILES

COc1cc2cc([nH]c2c(OC)c1OC)C(=O)N1C[C@@H](CCl)c2c1cc(O)c1ccccc21
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Uddin MJ, et al. Synthesis of 5- and 6-carboxy-X-rhodamines. Org Lett. 2008 Nov 6;10(21):4799-801.

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