Cart
sales@molnova.com
Busulfan
CAS No. 55-98-1
Busulfan( Busulphan | Mielosan | Milecitan | Myeloleukon | Mylecytan | Myleran | NCI C01592 | NSC 750 )
Catalog No. M15037 CAS No. 55-98-1
Busulfan is a bifunctional alkylating agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 41 | In Stock |
|
| 1G | 56 | In Stock |
|
Biological Information
-
Product NameBusulfan
-
NoteResearch use only, not for human use.
-
Brief DescriptionBusulfan is a bifunctional alkylating agent.
-
DescriptionBusulfan is a bifunctional alkylating agent.
-
In VitroWestern Blot Analysis Cell Line:WI38 cells Concentration:120 μM Incubation Time:24 hours Result:Incited a moderate p53 activation, but strong Erk, p38, and JNK phosphorylation, in a time-dependent manner. Elicited an immediate up-regulation of p21 expression, which subsided by day 11.
-
In VivoAnimal Model:ICR male mice ranging in age from 8 to 12 weeks (30-40 g) Dosage:40 mg/kg (in sesame oil) Administration:IP; single dose Result:Increased apoptosis and decreased the testis weight in mice. Exhibited higher level of pRB expression, inhibited Rb phosphorylation and PCNA expression compared to the control.
-
SynonymsBusulphan | Mielosan | Milecitan | Myeloleukon | Mylecytan | Myleran | NCI C01592 | NSC 750
-
PathwayCell Cycle/DNA Damage
-
TargetDNA Alkylator
-
RecptorDNA Alkylation
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number55-98-1
-
Formula Weight246.3
-
Molecular FormulaC6H14O6S2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 49 mg/mL (198.94 mM)
-
SMILESCS(=O)(OCCCCOS(C)(=O)=O)=O
-
Chemical Namebutane-1,4-diyl dimethanesulfonate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Meng A, et al. Y Res, 2003, 63(17), 5414-5419.
molnova catalog
related products
-
Temozolomide
An alkylating agent used as a treatment of some brain cancers, astrocytoma and glioblastoma.
-
Crystal Violet
Crystal violet is a triarylmethane dye.
-
Oxaliplatin
A platinum-based antineoplastic agent that works by blocking the duplication of DNA; forms both inter- and intra-strand cross links in DNA, prevents DNA replication and transcription, causing cell death.
