Dehydronitrosonisoldipine
CAS No. 87375-91-5
Dehydronitrosonisoldipine( —— )
Catalog No. M26148 CAS No. 87375-91-5
Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 124 | In Stock |
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| 2MG | 69 | In Stock |
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| 5MG | 126 | In Stock |
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| 10MG | 178 | In Stock |
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| 25MG | 306 | In Stock |
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| 50MG | 427 | In Stock |
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| 100MG | 551 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | 1097 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDehydronitrosonisoldipine
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NoteResearch use only, not for human use.
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Brief DescriptionDehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders.
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DescriptionDehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.(In Vitro):Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the sterile α and TIR motif-containing 1-dN-expression cells, and decreases the cellular cADPR.
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In VitroDehydronitrosonisoldipine exhibits an IC50 of 4 μM in the SARM1-dN-expression cells, and decreases the cellular cADPR in cells expressing SARM1, but not in expressing SAM-TIR cells.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetCalcium Channel
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number87375-91-5
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Formula Weight370.4
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Molecular FormulaC20H22N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (269.98 mM)
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SMILESCOC(=O)c1c(C)nc(C)c(C(=O)OCC(C)C)c1-c1ccccc1N=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Pinaverium bromide
Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain diarrhea and intestinal discomfort.
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DS16570511
DS16570511 is a cellular osmotic inhibitor of mitochondrial calcium monoab, which blocks MCU or MICU1-dependent Ca2+ influx.DS16570511 dose - dependent inhibition of serum-induced mitochondrial Ca2+ influx in HEK293A cells with IC50 of 7 M.DS16570511 inhibits the uptake of isolated Ca2+. mitochondria from human cells, rat heart and pig heart.
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MMK 1
Potent and selective human formyl peptide receptor FPR2 agonist (EC50 values are 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Induces migration of human monocytes and neutrophils via a chemotactic mechanism and enhances production of proinflammatory cytokines IL-1β and IL-6. Also activates the neutrophil superoxide-generating NADPH-oxidase.
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