Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - MMP - ARP-100

ARP-100

CAS No. 704888-90-4

ARP-100( MMP-2 Inhibitor III | ARP100 )

Catalog No. M24720 CAS No. 704888-90-4

ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 67 In Stock
5MG 61 In Stock
10MG 93 In Stock
25MG 188 In Stock
50MG 346 In Stock
100MG 555 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    ARP-100
  • Note
    Research use only, not for human use.
  • Brief Description
    ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM)
  • Description
    ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 shows the less inhibitory activity towards MMP-1 (>50 μM), MMP-3 (4.5 μM), MMP-7 (>50 μM), and MMP-9 (0.2 μM).
  • In Vitro
    ARP-100 (50 nM) shows a significant reduction in the total number of invasive elongations.
  • In Vivo
    ——
  • Synonyms
    MMP-2 Inhibitor III | ARP100
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP-2|MMP-9|MMP-3|MMP-1|MMP-7
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    704888-90-4
  • Formula Weight
    364.42
  • Molecular Formula
    C17H20N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:96 mg/mL?(263.43 mM;?Need ultrasonic)
  • SMILES
    CC(C)ON(CC(NO)=O)S(c(cc1)ccc1-c1ccccc1)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rossello A, et al. New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2). Bioorg Med Chem. 2004 May 1;12(9):2441-50.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Incyclinide

    Incyclinide is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.

  • Tanomastat

    Tanomastat (BAY 129566) is a potent,orally available, non-peptidic inhibitor of MMP-2, MMP-3 and MMP-9 with 11, 143 and 301 nM, respectively.

  • Acetohydroxamic acid

    Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea.

Sign In Join Free