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m-PEG7-4-nitrophenyl carbonate

CAS No. 678150-56-6

m-PEG7-4-nitrophenyl carbonate( —— )

Catalog No. M24690 CAS No. 678150-56-6

m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    m-PEG7-4-nitrophenyl carbonate
  • Note
    Research use only, not for human use.
  • Brief Description
    m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PEGs|Alkyl/ether
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    678150-56-6
  • Formula Weight
    461.46
  • Molecular Formula
    C20H31NO11
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    COCCOCCOCCOCCOCCOCCOC(OC1=CC=C([N+]([O-])=O)C=C1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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