BSJ-03-123

CAS No. 2361493-16-3

BSJ-03-123( —— )

Catalog No. M21744 CAS No. 2361493-16-3

BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 116 In Stock
5MG 187 In Stock
10MG 274 In Stock
25MG 432 In Stock
50MG 578 In Stock
100MG 826 In Stock
200MG Get Quote In Stock
500MG 1665 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BSJ-03-123
  • Note
    Research use only, not for human use.
  • Brief Description
    BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
  • Description
    BSJ-03-123 is a potent and novel CDK6-selective small-molecule degrader (PROTAC).
  • In Vitro
    BSJ-03-123 (BSJ) causes a pronounced anti-proliferative effect in CDK6-dependent AML cell lines by inducing a G1 cell-cycle arrest without a measurable increase in apoptosis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2361493-16-3
  • Formula Weight
    937.01
  • Molecular Formula
    C??H??N??O??
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (106.72 mM)
  • SMILES
    O=C(C(C(C)=O)=C1C)N(C2CCCC2)C3=C1C=NC(NC4=CC=C(N5CCN(CCOCCOCCOCCNC(COC6=CC=CC7=C6C(N(C8C(NC(CC8)=O)=O)C7=O)=O)=O)CC5)C=N4)=N3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Brand M, et al. Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML. Cell Chem Biol. 2019 Feb 21;26(2):300-306.e9.
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