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dBRD9
CAS No. 2170679-45-3
dBRD9( dBRD 9 )
Catalog No. M13465 CAS No. 2170679-45-3
dBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 434 | In Stock |
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| 5MG | 312 | In Stock |
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| 10MG | 502 | In Stock |
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| 25MG | 874 | In Stock |
|
| 50MG | 1293 | In Stock |
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| 100MG | 1795 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamedBRD9
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NoteResearch use only, not for human use.
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Brief DescriptiondBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex.
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DescriptiondBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex; exhibits markedly enhanced potency compared to parental ligands (10-100 fold).
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In VitroWestern Blot Analysis Cell Line:MOLM-13 cells.Concentration:0.5, 5, 50, 500 and 5000 nM.Incubation Time:4 h.Result:Reduced the expression of BRD9.
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In Vivo——
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SynonymsdBRD 9
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PathwayPROTACs
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TargetPROTAC
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RecptorPROTAC
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Research Area——
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Indication——
Chemical Information
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CAS Number2170679-45-3
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Formula Weight783.839
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Molecular FormulaC40H45N7O10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (127.58 mM)
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SMILESO=C(NCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)C
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Chemical Name2-((2,6-dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Remillard D, et al. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743.
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