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Galloflavin

CAS No. 568-80-9

Galloflavin( —— )

Catalog No. M24558 CAS No. 568-80-9

Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Galloflavin
  • Note
    Research use only, not for human use.
  • Brief Description
    Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively.
  • Description
    Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 μM and 15.06 μM, respectively. Galloflavin is also a potential anticancer agent.
  • In Vitro
    Galloflavin effectively inhibits cell growth in endometrial cancer cell lines and primary cultures of human endometrial cancer through its involvement in multiple signaling pathways that regulate metabolism, cell cycle, apoptosis, cell stress and metastasis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    LDH
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    568-80-9
  • Formula Weight
    278.17
  • Molecular Formula
    C12H6O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:1.9 mg/ml (6.83 mM)
  • SMILES
    OC(C=C1OC(C2=CC3=O)=O)=C(O)OC1=C2C(O)=C3O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Manerba M, Vettraino M, Fiume L, Di Stefano G, Sartini A, Giacomini E, Buonfiglio R, Roberti M, Recanatini M. Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase. ChemMedChem. 2012 Feb 6;7(2):311-7.
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