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hDHODH-IN-1
CAS No. 1173715-42-8
hDHODH-IN-1( —— )
Catalog No. M26247 CAS No. 1173715-42-8
hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 71 | In Stock |
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| 5MG | 65 | In Stock |
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| 10MG | 105 | In Stock |
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| 25MG | 211 | In Stock |
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| 50MG | 300 | In Stock |
|
| 100MG | 418 | In Stock |
|
| 200MG | 564 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamehDHODH-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionhDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.
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DescriptionhDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.(In Vitro):Dihydroorotate dehydrogenase (DHODH) is a class-2 dihydroorotate dehydrogenase in human. Inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers,inflammatory diseases , and autoimmune and multiple sclerosis because DHODH is required to ensure proliferating-cell viability.
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In VitroHuman dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorPEGs
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Research Area——
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Indication——
Chemical Information
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CAS Number1173715-42-8
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Formula Weight278.311
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Molecular FormulaC17H14N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (898.28 mM)
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SMILESC\C(O)=C(/C#N)C(=O)Nc1ccc(cc1)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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