Saikogenin A( —— )

Catalog No. M24472 CAS No. 5092-09-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Saikogenin A
Note

Research use only, not for human use.
Brief Description

Saikogenin A is a dipeptidyl peptidase-4 inhibitor.
Description

Saikogenin A is a dipeptidyl peptidase-4 inhibitor.
In Vitro

Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide.
In Vivo

Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation.
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

DPP
Recptor

DPP-4
Research Area

——
Indication

——

CAS Number

5092-09-1
Formula Weight

472.7
Molecular Formula

C30H48O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 25 mg/mL (52.89 mM)
SMILES

CC(C)(CC[C@]12CO)CC1=C1C=C[C@H]([C@@](C)(CC3)[C@@H](CC4)[C@](C)(CO)[C@H]3O)[C@]4(C)[C@]1(C)C[C@@H]2O
Chemical Name

——

1.Pharmaceutical application of saikogenin A. CN107375300A.

Calculator

molnova catalog