Desoxypeganine

CAS No. 495-59-0

Desoxypeganine( Deoxypeganine )

Catalog No. M24453 CAS No. 495-59-0

Desoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Desoxypeganine
  • Note
    Research use only, not for human use.
  • Brief Description
    Desoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.
  • Description
    Desoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.Desoxypeganine is being developed for its potential utility in the pharmacological treatment of alcohol abuse to reduce craving and depression in alcohol abusers, and might also be useful as a smoking cessation aid.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Female Alko alcohol (AA) rats (Thirty eight adult) Dosage:10, 20, 30 mg/kg Administration:Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days Result:Abolished ethanol preference.
  • Synonyms
    Deoxypeganine
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    AChE
  • Recptor
    cholinesterase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    495-59-0
  • Formula Weight
    172.23
  • Molecular Formula
    C11H12N2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    C1CC2=NC3=CC=CC=C3CN2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Herraiz T , H Guillén, VJ Arán, et al. Identification, occurrence and activity of quinazoline alkaloids in Peganum harmala[J]. Food and Chemical Toxicology, 2017, 103:261.
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