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Irisolidone
CAS No. 2345-17-7
Irisolidone( —— )
Catalog No. M24066 CAS No. 2345-17-7
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 269 | In Stock |
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| 5MG | 264 | In Stock |
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| 10MG | 398 | In Stock |
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| 25MG | 653 | In Stock |
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| 50MG | 888 | In Stock |
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| 100MG | 1190 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIrisolidone
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NoteResearch use only, not for human use.
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Brief DescriptionIrisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
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DescriptionIrisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.
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In VitroIrisolidone, an isoflavone metabolite, represses JC virus gene expression via inhibition of Sp1 binding in human glial cells.Irisolidone can inhibit endothelial cell proliferation.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetChloride Channel
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RecptorVRAC|IL Receptor|NF-Κb
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Research Area——
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Indication——
Chemical Information
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CAS Number2345-17-7
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Formula Weight314.29
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Molecular FormulaC17H14O6
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=C(OC)C(O)=C13
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Natural and synthetic flavonoids, novel blockers of the volume-regulated anion channels, inhibit endothelial cell proliferation.Pflugers Arch. 2018 Jun 30.
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