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S-(5'-Adenosyl)-L-methionine tosylate
S-(5'-Adenosyl)-L-methionine tosylate
CAS No. 52248-03-0
S-(5'-Adenosyl)-L-methionine tosylate( —— )
Catalog No. M18717 CAS No. 52248-03-0
S-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 31 | In Stock |
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| 10MG | 29 | In Stock |
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| 25MG | 44 | In Stock |
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| 50MG | 62 | In Stock |
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| 100MG | 81 | In Stock |
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| 200MG | 127 | In Stock |
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| 500MG | 258 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameS-(5'-Adenosyl)-L-methionine tosylate
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NoteResearch use only, not for human use.
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Brief DescriptionS-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.
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DescriptionS-(5'-Adenosyl)-L-methionine (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases. SAM (tosylate) (SAMe) is a stable salt of SAM that is included in nutritional supplements for oral use. SAMe reportedly ameliorates depression, pain associated with osteoarthritis and fibromyalgia, and liver toxicity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetChloride Channel
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number52248-03-0
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Formula Weight570.64
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Molecular FormulaC22H30N6O8S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 150 mg/mL (262.86 mM)
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SMILESCc1ccc(cc1)S([O-])(=O)=O.C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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NS1652
NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.NS1652 (20 μM) fully and reversibly inhibits the red cell Cl-conductance. NS1652 effectively inhibits the chloride conductance (IC50, 1.6 μM) in human and mouse red blood cells, but only weakly inhibits VRAC (IC50, 125 μM) in HEK293 cells. NS1652 markedly blocks the NO production (IC50: 3.1 μM in BV2 cells).
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DRAinh-A250
DRAinh-A250 is a specific inhibitor of Cl-/anion exchanger SLC26A3 (DRA).
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