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Eact
CAS No. 461000-66-8
Eact( —— )
Catalog No. M24413 CAS No. 461000-66-8
Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
|
| 2MG | 41 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 122 | In Stock |
|
| 25MG | 254 | In Stock |
|
| 50MG | 420 | In Stock |
|
| 100MG | 618 | In Stock |
|
| 200MG | 881 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEact
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NoteResearch use only, not for human use.
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Brief DescriptionEact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
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DescriptionEact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetChloride Channel
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RecptorTMEM16A
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Research Area——
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Indication——
Chemical Information
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CAS Number461000-66-8
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Formula Weight428.5
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Molecular FormulaC22H24N2O5S
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (116.69 mM; Need ultrasonic)
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SMILESCOCCN(C1=NC(=CS1)C2=CC=CC=C2)C(=O)C3=CC(=C(C(=C3)OC)OC)OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu S, et al. Eact, a small molecule activator of TMEM16A, activates TRPV1 and elicits pain- and itch-related behaviours. Br J Pharmacol. 2016 Apr;173(7):1208-18.
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