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NTP42
CAS No. 2055599-51-2
NTP42( —— )
Catalog No. M23921 CAS No. 2055599-51-2
NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 154 | In Stock |
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| 2MG | 79 | In Stock |
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| 5MG | 136 | In Stock |
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| 10MG | 215 | In Stock |
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| 25MG | 364 | In Stock |
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| 50MG | 529 | In Stock |
|
| 100MG | 759 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNTP42
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NoteResearch use only, not for human use.
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Brief DescriptionNTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
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DescriptionNTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM) .
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In Vitro——
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In VivoAnimal Model:Male Wistar-Kyoto rats Dosage:0.25 mg/kg BID Administration:28-day drug treatment was initiated within 24 h post-MCT (60 mg/kg)Result:Reduced the MCT-induced PAH, including mPAP and RSVP.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPPAR
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RecptorTXA2R
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Research Area——
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Indication——
Chemical Information
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CAS Number2055599-51-2
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Formula Weight515.53
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Molecular FormulaC25H23F2N3O5S
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Purity>98% (HPLC)
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SolubilityDMSO:30mg/mL (58.19 mM; Need ultrasonic)
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SMILESCC(C)(C)NC(NS(c(cc(cc1)C#N)c1Oc1cc(-c(cc2)ccc2OC(F)F)ccc1)(=O)=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.B. Therese KINSELLA, et al. Thromboxane receptor antagonists. WO2016203314A1.
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