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NTP42

CAS No. 2055599-51-2

NTP42( —— )

Catalog No. M23921 CAS No. 2055599-51-2

NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	129	In Stock
10MG	203	In Stock
25MG	345	In Stock
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100MG	734	In Stock
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Biological Information

Product Name

NTP42
Note

Research use only, not for human use.
Brief Description

NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
Description

NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM) .
In Vitro

——
In Vivo

Animal Model:Male Wistar-Kyoto rats Dosage:0.25 mg/kg BID Administration:28-day drug treatment was initiated within 24 h post-MCT (60 mg/kg)Result:Reduced the MCT-induced PAH, including mPAP and RSVP.
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

PPAR
Recptor

TXA2R
Research Area

——
Indication

——

Chemical Information

CAS Number

2055599-51-2
Formula Weight

515.53
Molecular Formula

C25H23F2N3O5S
Purity

>98% (HPLC)
Solubility

DMSO:30mg/mL (58.19 mM; Need ultrasonic)
SMILES

CC(C)(C)NC(NS(c(cc(cc1)C#N)c1Oc1cc(-c(cc2)ccc2OC(F)F)ccc1)(=O)=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.B. Therese KINSELLA, et al. Thromboxane receptor antagonists. WO2016203314A1.

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