DD1
CAS No. 187585-11-1
DD1( 3,3'-Diamino-4'-methoxyflavone | HUN85111 )
Catalog No. M23854 CAS No. 187585-11-1
DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 300 | In Stock |
|
| 10MG | 509 | In Stock |
|
| 25MG | 802 | In Stock |
|
| 50MG | 1107 | In Stock |
|
| 100MG | 1503 | In Stock |
|
| 500MG | 3015 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDD1
-
NoteResearch use only, not for human use.
-
Brief DescriptionDD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
-
DescriptionDD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
-
In VitroDD1 (20 μM; 96 h) shows antiproliferation activity in a dose- and time-dependent manner in U937 cells.DD1 induces cell cycle arrest at G2/M phase and apoptosis.DD1 (10, 20 μM; 48 h) induces mitochondrial membrane depolarization, Bax upregulation and Bad dephosphorylation.DD1 (2-20 μM; 40 h) shows inhibitor for chymotrypsin-like activity in U937 lysates.
-
In Vivo——
-
Synonyms3,3'-Diamino-4'-methoxyflavone | HUN85111
-
PathwayProteasome/Ubiquitin
-
TargetProteasome
-
Recptorproteasome
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number187585-11-1
-
Formula Weight282.29
-
Molecular FormulaC16H14N2O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOC1=C(C=C(C=C1)C2=C(C(=O)C3=CC=CC=C3O2)N)N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
MLN9708
A potent, selective, orally bioavailable proteasome inhibitor with IC50 of 3.4 nM.
-
MG-115
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively.
-
YU-101
A potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely.
Cart
sales@molnova.com