SR 142948( —— )

Catalog No. M23837 CAS No. 184162-64-9

SR 142948 is a neurotensin (NT) receptor antagonist.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

SR 142948
Note

Research use only, not for human use.
Brief Description

SR 142948 is a neurotensin (NT) receptor antagonist.
Description

SR 142948 is a neurotensin (NT) receptor antagonist.
In Vitro

——
In Vivo

Animal Model:Female Swiss albino CD1 mice (25-30 g; intrastriatal injection of 10 pg/mouse NT).Dosage:2 μg/kg Administration:Oral administration; single.Result:Inhibited the turning behavior with maximal and significant antagonism between 1-2 h after administration.
Synonyms

——
Pathway

GPCR/G Protein
Target

Neurotensin Receptor
Recptor

Neurotensin Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

184162-64-9
Formula Weight

685.86
Molecular Formula

C39H51N5O6
Purity

>98% (HPLC)
Solubility

DMSO:Soluble
SMILES

COc1cccc(OC)c1-c1cc(nn1-c1ccc(cc1C(C)C)C(=O)N(C)CCCN(C)C)C(=O)NC1(C2CC3CC(C2)CC1C3)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.L Quéré, Longfils G , Boigegrain R , et al. X-ray structural characterization of SR 142948, a novel potent synthetic neurotensin receptor antagonist[J]. Bioorganic & Medicinal Chemistry Letters, 1998, 8(6):653-658.

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