MONNA
CAS No. 1572936-83-4
MONNA( —— )
Catalog No. M23684 CAS No. 1572936-83-4
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | In Stock |
|
| 10MG | 115 | In Stock |
|
| 25MG | 260 | In Stock |
|
| 50MG | 410 | In Stock |
|
| 100MG | 591 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMONNA
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NoteResearch use only, not for human use.
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Brief DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM).
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DescriptionMONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetChloride Channel
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RecptorTMEM16A
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Research Area——
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Indication——
Chemical Information
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CAS Number1572936-83-4
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Formula Weight338.31
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Molecular FormulaC18H14N2O5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCOC1=CC(=CC2=CC=CC=C21)NC3=C(C=C(C=C3)[N+](=O)[O-])C(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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IAA-94
IAA-94 is an indanyloxyacetic acid (IAA) inhibitor of epithelial chloride channels that binds channels in bovine kidney cortex microsomes with Ki of 1 uM.
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Fenamic acid
Fenamic acid is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including flufenamic acid, tolfenamic acid, mefenamic acid, and meclofenamic acid.
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GaTx2
Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.2.
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