Pomolic acid

CAS No. 13849-91-7

Pomolic acid( —— )

Catalog No. M23539 CAS No. 13849-91-7

Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 325 In Stock
5MG 282 In Stock
10MG 407 In Stock
25MG 663 In Stock
50MG 974 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Pomolic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities.
  • Description
    Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways.
  • In Vitro
    Randialic acid A (Pomolic acid) induces apoptosis ofGBM cells as demonstrated by DNA fragmentation. ?Pomolic acid-induced apoptosis is dependent on reactive oxygen species (ROS) production. It also induces uncoupling of mitochondria membrane potential and activation of caspase-3 and -9.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    PKA
  • Recptor
    AMPK|Apoptosis|Caspase|HIV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    13849-91-7
  • Formula Weight
    472.7
  • Molecular Formula
    C30H48O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (211.55 mM)
  • SMILES
    C[C@H](CC[C@]1([C@@H]2C3=CC[C@H]([C@@](C)(CC4)[C@@H](CC5)C(C)(C)[C@H]4O)[C@]5(C)[C@]3(C)CC1)C(O)=O)[C@@]2(C)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Anti-AIDS agents. 30. Anti-HIV activity of oleanolic acid, pomolic acid, and structurally related triterpenoids.J Nat Prod. 1998 Sep;61(9):1090-5.
molnova catalog
related products
  • GUANOSINE 3':5'-CYCL...

    GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE also known as cGMP is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones including acetylcholine insulin and oxytocin.

  • Hydroxyfasudil

    Hydroxyfasudil is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).

  • AP-C2

    AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.