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H-9 dihydrochloride
CAS No. 116700-36-8
H-9 dihydrochloride( —— )
Catalog No. M33864 CAS No. 116700-36-8
H-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 46 | Get Quote |
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| 5MG | 63 | Get Quote |
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| 10MG | 91 | Get Quote |
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| 25MG | 145 | Get Quote |
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| 50MG | 217 | Get Quote |
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| 100MG | 314 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameH-9 dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionH-9 dihydrochloride is a potent protein kinase (PKA) inhibitor.H-9 Dihydrochloride significantly reduces the excitatory response to 5-HT at low concentrations.
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DescriptionH-9 Dihydrochloride is a PKA (protein kinase) inhibitor. H-9 Dihydrochloride (10 μM) significantly reduces the excitatory response to 5-HT. H-9 Dihydrochloride also has a direct effect on pharyngeal activity. H-9 Dihydrochloride inhibits signal-transduction and cell growth in EGF (epidermal growth factor)-dependent epithelial cell lines.
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In VitroH-9 Dihydrochloride significantly inhibits A431 cells.H-9 Dihydrochloride inhibits more effectively cyclic nucleotide-dependent protein kinases than other kinases.
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In VivoH-9 Dihydrochloride microperfusion (100 μM) prevents picrotoxin seizures in 50% of the animals and significantly reduced the mean number of seizures and mean seizure duration.
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Synonyms——
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PathwayApoptosis
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TargetPKA
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RecptorPKA | EGFR | 5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number116700-36-8
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Formula Weight324.23
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Molecular FormulaC11H15Cl2N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(NCCN)(C1=CC=CC2=C1C=CN=C2)=O.Cl.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ito M, et al. A potent inhibitor of protein kinase C inhibits natural killer activity. Int J Immunopharmacol. 1988;10(3):211-6. ?
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