Lys-SMCC-DM1

CAS No. 1281816-04-3

Lys-SMCC-DM1( Lys-Nε-MCC-DM1 )

Catalog No. M23445 CAS No. 1281816-04-3

DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 1131 In Stock
5MG 656 In Stock
10MG 947 In Stock
25MG 1406 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Lys-SMCC-DM1
  • Note
    Research use only, not for human use.
  • Brief Description
    DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1.
  • Description
    DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Lys-Nε-MCC-DM1
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1281816-04-3
  • Formula Weight
    1103.71
  • Molecular Formula
    C53H75ClN6O15S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (90.60 mM)
  • SMILES
    C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)NCCCC[C@@H](C(=O)O)N)C)\C)OC)(NC(=O)O2)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
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