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Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - Lys-SMCC-DM1

Lys-SMCC-DM1

CAS No. 1281816-04-3

Lys-SMCC-DM1( Lys-Nε-MCC-DM1 )

Catalog No. M23445 CAS No. 1281816-04-3

DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 1131 In Stock
5MG 656 In Stock
10MG 947 In Stock
25MG 1406 In Stock
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Biological Information

  • Product Name
    Lys-SMCC-DM1
  • Note
    Research use only, not for human use.
  • Brief Description
    DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1.
  • Description
    DM1 is a tubulin inhibitor. Lys-SMCC-DM1 is the active metabolite of DM1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Lys-Nε-MCC-DM1
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1281816-04-3
  • Formula Weight
    1103.71
  • Molecular Formula
    C53H75ClN6O15S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (90.60 mM)
  • SMILES
    C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)NCCCC[C@@H](C(=O)O)N)C)\C)OC)(NC(=O)O2)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
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