ELOVL6-IN-2

Research use only, not for human use.

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.

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Animal Model:Male C57BL/6J mice Dosage:0.1~1mg/kg Administration:P.o Result:Potently and dose-proportionally suppressed the elongation index in the liver.Animal Model:Male C57BL/6J mice Dosage:10 mg/kg Administration:P.o Result:Demonstrated highly liver penetrable.Animal Model:Male C57BL/6J mice Dosage:1 mg/kg Administration:P.o Result:Exhibited sustained plasma exposure.

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Others

Other Targets

ELOVL6

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1067647-43-1

579.49

C28H23F6N3O4

>98% (HPLC)

DMSO:90mg/ml(155.31mM; Need ultrasonic)

CC(C)(CC(N1c2ccccc2)=C2C(C(F)(F)F)(C(C3=O)=C(C)NN3c(cc3)ccc3OC(F)(F)F)C1=O)CC2=O

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(-20℃)

With Ice Pack

≥ 2 years