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Glucocorticoid receptor agonist-1
CAS No. 2166375-82-0
Glucocorticoid receptor agonist-1( —— )
Catalog No. M34988 CAS No. 2166375-82-0
Glucocorticoid receptor agonist-1, a potent glucocorticoid receptor agonist, has an IC50 of 2.8 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 218 | In Stock |
|
| 5MG | 173 | In Stock |
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| 10MG | 278 | In Stock |
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| 25MG | 554 | In Stock |
|
| 50MG | 867 | In Stock |
|
| 100MG | 1386 | In Stock |
|
| 200MG | 1832 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGlucocorticoid receptor agonist-1
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NoteResearch use only, not for human use.
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Brief DescriptionGlucocorticoid receptor agonist-1, a potent glucocorticoid receptor agonist, has an IC50 of 2.8 nM.
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DescriptionGlucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41.
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In VitroGlucocorticoid receptor agonist immunoconjugates are useful for treating autoimmune diseases such as, but not limited to, rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult Crohn's disease, pediatric Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, uveitis, Behcets disease, a spondyloarthropathy, or psoriasis.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGlucocorticoid Receptor | ADC Cytotoxin
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Research Area——
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Indication——
Chemical Information
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CAS Number2166375-82-0
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Formula Weight569.69
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Molecular FormulaC35H39NO6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (175.53 mM; Ultrasonic )
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SMILES[H][C@]1(O[C@]2([H])C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO)c1ccc(Cc2cccc(N)c2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.
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