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IDO1-IN-5

CAS No. 2166616-75-5

IDO1-IN-5( —— )

Catalog No. M22853 CAS No. 2166616-75-5

IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	65	In Stock
2MG	46	In Stock
5MG	75	In Stock
10MG	126	In Stock
25MG	215	In Stock
50MG	338	In Stock
100MG	528	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

IDO1-IN-5
Note

Research use only, not for human use.
Brief Description

IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
Description

IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
In Vitro

LY-3381916 (IDO1-IN-5) (up to 100 μM) shows no obvious agonism of aryl hydrocarbon receptor (AHR).
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

IDO
Recptor

IDO1
Research Area

——
Indication

——

Chemical Information

CAS Number

2166616-75-5
Formula Weight

396.45
Molecular Formula

C23H25FN2O3
Purity

>98% (HPLC)
Solubility

DMSO:300 mg/mL (756.72 mM; Need ultrasonic)
SMILES

FC1=CC=C(C(N[C@H](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).

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