Cart
sales@molnova.com
IDO1-IN-5
CAS No. 2166616-75-5
IDO1-IN-5( —— )
Catalog No. M22853 CAS No. 2166616-75-5
IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | In Stock |
|
| 5MG | 71 | In Stock |
|
| 10MG | 120 | In Stock |
|
| 25MG | 203 | In Stock |
|
| 50MG | 327 | In Stock |
|
| 100MG | 511 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameIDO1-IN-5
-
NoteResearch use only, not for human use.
-
Brief DescriptionIDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
-
DescriptionIDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
-
In VitroLY-3381916 (IDO1-IN-5) (up to 100 μM) shows no obvious agonism of aryl hydrocarbon receptor (AHR).
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetIDO
-
RecptorIDO1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2166616-75-5
-
Formula Weight396.45
-
Molecular FormulaC23H25FN2O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:300 mg/mL (756.72 mM; Need ultrasonic)
-
SMILESFC1=CC=C(C(N[C@H](C)C2=CC=C(N(C(C3CCOCC3)=O)CC4)C4=C2)=O)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).
molnova catalog
related products
-
IDO-IN-1
IDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)
-
Chelidonine
Chelidonine isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways.
-
IDO-IN-13
IDO-IN-13 is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).
