Flemiphilippinin D

CAS No. 99119-72-9

Flemiphilippinin D( Kushenol E? )

Catalog No. M21536 CAS No. 99119-72-9

Kushenol E is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM Ki: 9.5 μM) has anti-tumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Flemiphilippinin D
  • Note
    Research use only, not for human use.
  • Brief Description
    Kushenol E is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM Ki: 9.5 μM) has anti-tumor activity.
  • Description
    Kushenol E is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM Ki: 9.5 μM) has anti-tumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Kushenol E?
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    IDO
  • Recptor
    IDO1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    99119-72-9
  • Formula Weight
    424.5
  • Molecular Formula
    C25H28O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)=CCc(c(O)c(CC=C(C)C)c(O[C@@H](C1)c(ccc(O)c2)c2O)c2C1=O)c2O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kwon M et al. Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 23-dioxygenase 1 activity. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1481-1488.
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