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IDO-IN-1
CAS No. 914638-30-5
IDO-IN-1( —— )
Catalog No. M20700 CAS No. 914638-30-5
IDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 125 | In Stock |
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| 5MG | 178 | In Stock |
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| 10MG | 320 | In Stock |
|
| 25MG | 531 | In Stock |
|
| 50MG | 773 | In Stock |
|
| 100MG | 1062 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIDO-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionIDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)
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DescriptionIDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)
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In VitroIDO-IN-1 (Compound 5m) is a potent (HeLa IC50=12 nM) inhibitor of IDO.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetIDO
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RecptorIDO
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Research Area——
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Indication——
Chemical Information
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CAS Number914638-30-5
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Formula Weight316.09
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Molecular FormulaC9H7BrFN5O2
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Purity>98% (HPLC)
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SolubilityDMSO:682 mg/mL (2157.61 mM)
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SMILESNc1nonc1C(Nc1ccc(F)c(Br)c1)=NO
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Chemical Name(Z)-4-amino-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-125-oxadiazole-3-carboximidamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Discovery of Potent Competitive Inhibitors of Indoleamine 23-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model[J]. Journal of Medicinal Chemistry 2009 52(23):7364-7367.
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