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IDO-IN-1

CAS No. 914638-30-5

IDO-IN-1( —— )

Catalog No. M20700 CAS No. 914638-30-5

IDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 112 In Stock
5MG 98 In Stock
10MG 158 In Stock
25MG 283 In Stock
50MG 418 In Stock
100MG 586 In Stock
200MG 789 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    IDO-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    IDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)
  • Description
    IDO-IN-1 is a potent indoleamine 23-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays respectively.)
  • In Vitro
    IDO-IN-1 (Compound 5m) is a potent (HeLa IC50=12 nM) inhibitor of IDO.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    IDO
  • Recptor
    IDO
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    914638-30-5
  • Formula Weight
    316.09
  • Molecular Formula
    C9H7BrFN5O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:682 mg/mL (2157.61 mM)
  • SMILES
    Nc1nonc1C(Nc1ccc(F)c(Br)c1)=NO
  • Chemical Name
    (Z)-4-amino-N'-(3-bromo-4-fluorophenyl)-N-hydroxy-125-oxadiazole-3-carboximidamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Discovery of Potent Competitive Inhibitors of Indoleamine 23-Dioxygenase with in Vivo Pharmacodynamic Activity and Efficacy in a Mouse Melanoma Model[J]. Journal of Medicinal Chemistry 2009 52(23):7364-7367.
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